Causes:
Trauma 90% (increased incidence in periorbital trauma)
Nontraumatic - Increased CSF pressure or primary nontraumatic CSF leaks
Sites:
Most common cribriform plate and ethmoid air cells
Frontal sinus
Sella turcica
Sphenoid sinus
Lateral lamella of cribriform plate
Posterior ethmoid roof near anterior and medial sphenoid wall
Natural history:
Most of CSF leaks resolve spontaneously
CSF fistulae > 7 days - increased risk of meningitis
Diagnosis:
Beta-2 transferrin assay is the test of choice (high sensitivity and specificity)
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Although I have taken care to make my blog posts as accurately as possible, the blog itself is not replacement for text-books and journals. The blogger does not accept any harm or injury related to the use of the material from this blog. All the images are from my collection and are not copyrighted; hence feel free to use them and I do not want any credit also. The notes are from the quoted journals and text-books, relevant to my practice. If anybody feels I am violating copyright, please let me know. I will delete the relevant data from my blog. I am greatly indebted to the reference book Som PM et al, Head and Neck Imaging. 4th edition. Mosby publications. Unless given the reference, the reference is most likely to this book.
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